Inter use their strongest XI including Lautaro Martinez, Marcus Thuram and Federico Dimarco for the visit with some familiar faces in Monza.
It kicks off at the U-Power Stadium at 19.45 GMT.
The Nerazzurri were crowned Winter Champions, but have started to stutter lately with controversial goals allowing them to draw with Genoa and beat Verona.
Only a last-gasp missed penalty made the 2-1 result over Hellas stick, so with the Supercoppa Italiana coming up next week, Simone Inzaghi takes no chances with squad rotation.
Dimarco returns to take the left flank with Stefan de Vrij and Benjamin Pavard in defence, while new buy Tajon Buchanan is on the bench for the first time.
Monza are not quite the giant-killers of their debut Serie A season, but held Napoli and earned a thrilling 3-2 victory away to Frosinone in their last two games.
Goalkeeper Michele Di Gregorio is out for a month with a knee injury, joining Gianluca Caprari, Papu Gomez and Jose Machin on the absentee list.
New loan signing Daniel Maldini is on the bench, but former Inter players Danilo D’Ambrosio and Roberto Gagliardini start.
Valentin Carboni is on loan from the Inter youth academy and the 18-year-old has already contributed two goals and three assists in 12 Serie A appearances for Monza this season.
Andrea Colpani has been linked with both Inter and Milan moves for next term.
Monza: Sorrentino; D’Ambrosio, Gagliardini, Caldirola; Pereira, Pessina, Bondo, Ciurria; Colpani, V Carboni; Mota Carvalho
Inter: Sommer; Pavard, De Vrij, Bastoni; Darmian, Barella, Calhanoglu, Mkhitaryan, Dimarco; Lautaro Martinez, Thuram
Player statistic
| Andrea Colpani |  |
5' | ||
| 11' |  |
Hakan Calhanoglu | ||
| 14' |  |
Lautaro Martínez (Assist: Federico Dimarco) |
| 59' | |
Hakan Calhanoglu | ||
| 60' | |
Hakan Calhanoglu (Assist: Marcus Thuram) | ||
| Matteo Pessina | |
68' | ||
| Samuele Birindelli | |
70' | ||
| 77' | |
Benjamin Pavard | ||
| 84' | |
Lautaro Martínez | ||
| 88' | |
Marcus Thuram (Assist: Henrikh Mkhitaryan) |
Match statistic
