Dusan Vlahovic or Federico Chiesa may start on the bench against their former club Fiorentina this evening, while Vincenzo Italiano will look to Arthur in central midfield.
It kicks off at 19:45 GMT on Sunday.
Fiorentina are without the injured Gaetano Castrovilli, Dodo and Michael Kayode. Juventus loanee Arthur is set to start in the middle of the park alongside Alfred Duncan. The only doubt for the Tuscans appears to be on the left wing, with Christian Kouame and Josip Brekalo fighting for a spot.
Juventus have lost Timothy Weah due to a muscle injury, so the USMNT international has joined Mattia De Sciglio, Danilo and Alex Sandro on the sidelines, plus the suspended Nicolò Fagioli and Paul Pogba.
McKennie will, therefore, start as a right winger with Fabio Miretti, Manuel Locatelli and Adrien Rabiot in central midfield. Filip Kostic or Andrea Cambiaso will get the nod on the left wing.
Former Fiorentina striker Vlahovic and Chiesa are available and fit to play, but one may start from the bench. Massimiliano Allegri will take a final decision in the morning.
Fiorentina vs. Juventus – probable line-ups
Fiorentina (4-2-3-1): Terracciano; Parisi, Milenkovic, Quarta, Biraghi; Arthur, Duncan; Nico Gonzalez, Bonaventura, Brekalo; Beltran.
Juventus (4-4-2): Szczesny; Gatti, Bremer, Rugani; McKennie, Miretti, Locatelli, Rabiot, Cambiaso; Vlahovic, Kean.