Roma have the chance to close on Juventus and break away from Napoli, so start Seydou Doumbia and Gervinho against struggling Parma.
It kicks off at the Stadio Olimpico at 14.00 GMT, click here to follow our LIVEBLOG.
Napoli surprisingly lost 3-1 at Palermo last night, so a victory would enable the Giallorossi to open up a seven-point gap from third place.
Roma have the chance to close on Juventus and break away from Napoli, so start Seydou Doumbia and Gervinho against struggling Parma.
It kicks off at the Stadio Olimpico at 14.00 GMT, click here to follow our LIVEBLOG.
Napoli surprisingly lost 3-1 at Palermo last night, so a victory would enable the Giallorossi to open up a seven-point gap from third place.
They haven’t lost hope of catching up to leaders Juventus either, ending a run of four consecutive stalemates by beating Cagliari 2-1.
Miralem Pjanic had been due to start, but came down with flu symptoms overnight, the same issue affecting Francesco Totti.
Douglas Maicon, Victor Ibarbo, Juan Manuel Iturbe, Kevin Strootman, Leandro Castan and Federico Balzaretti are injured with Jose Holebas banned.
Gervinho and Seydou Doumbia are back after winning the African Cup of Nations for the Ivory Coast, thrown straight into the starting XI.
Parma are on their third owners in three months and tomorrow is the deadline for the club to pay outstanding wages stretching back to July 2014.
The players already have the paperwork ready to send the club into administration if that money is not provided on Monday.
This week the previous owner Tommaso Ghirardi was deferred to the Disciplinary Commission for unpaid wages up to September 2014, so Parma are likely to be docked further points.
Daniele Galloppa is suspended, while Massimo Gobbi, Cristobal Jorquera, Andi Lila and Jonathan Biabiany are unavailable.
Roma: De Sanctis; Florenzi, Manolas, Yanga-Mbiwa, Cole; Keita, De Rossi, Nainggolan; Gervinho, Doumbia, Ljajic
Parma: Mirante; Cassani, Costa, Lucarelli, Mendes; Mauri, Mariga, Nocerino; Varela, Belfodil, Rodriguez