Juventus look to Dejan Kulusevski, Federico Chiesa, Alvaro Morata and Cristiano Ronaldo against Genoa, who start future Bianconeri player Nicolò Rovella.
It kicks off at the Allianz Stadium in Turin at 14.00 UK time (13.00 GMT).
Juventus look to Dejan Kulusevski, Federico Chiesa, Alvaro Morata and Cristiano Ronaldo against Genoa, who start future Bianconeri player Nicolò Rovella.
It kicks off at the Allianz Stadium in Turin at 14.00 UK time (13.00 GMT).
The Bianconeri got back on track and climbed into third place with their rescheduled midweek 2-1 win over Napoli.
That was decided by Paulo Dybala coming off the bench to score, but La Joya is again not fit enough to start, so Morata partners Ronaldo with Kulusevski and Chiesa in support.
Leonardo Bonucci and Federico Bernardeschi are still out of action after contracting COVID on international duty with Italy.
Wojciech Szczesny returns to goal after he was surprisingly replaced by Gigi Buffon on Wednesday.
Genoa are relatively comfortable in mid-table, but not mathematically safe from the drop yet.
Kevin Strootman is suspended, with Luca Pellegrini and Lennart Czyborra injured, so 19-year-old Nicolò Rovella gets a rare start against his future club.
That’s because he has already been sold to Juve for €18m plus bonuses and left on loan with the Grifone until June 2022.
There are no rules in Italy on players facing their parent clubs, so he will take this as an opportunity to impress his next side.
So will goalkeeper Mattia Perin, who again is on loan from Juventus.
Gianluca Scamacca and Goran Pandev get the nod in attack, with Mattia Destro and Eldor Shomurodov on the bench.
Juventus: Szczesny; Cuadrado, De Ligt, Chiellini, Danilo; Kulusevski, Bentancur, Rabiot, Chiesa; Morata, Ronaldo
Genoa: Perin; Masiello, Radovanovic, Criscito; Biraschi, Rovella, Badelj, Behrami, Zappacosta; Pandev, Scamacca
Ref: Di Bello