On form Genoa and their Coach Gian Piero Gasperini want to take another scalp against Europa League chasing Inter.
It kicks off at 19.45 UK time (18.45 GMT), follow the action as it happens on our LIVEBLOG.
Going into the penultimate round of the season, Genoa are in sixth place and four points clear of Inter in eighth.
On form Genoa and their Coach Gian Piero Gasperini want to take another scalp against Europa League chasing Inter.
It kicks off at 19.45 UK time (18.45 GMT), follow the action as it happens on our LIVEBLOG.
Going into the penultimate round of the season, Genoa are in sixth place and four points clear of Inter in eighth.
This is a head-to-head for European qualification, but the Rossoblu might not be allowed in anyway because their application for a UEFA licence was rejected.
To add insult to injury, missing out could hand their spot to hated city rivals Sampdoria, who did fill out the paperwork correctly.
Gasperini also wants to prove a point against the club that famously sacked him only a few weeks into his tenure, while Rodrigo Palacio returns to his old hunting ground.
Genoa have injury problems, missing Diego Perotti, Lorenzo Ariaudo, M’Baye Niang and Marco Borriello.
Leonardo Pavoletti and Andrea Bertolacci have found their scoring touch in recent weeks, while Iago Falque is on spectacular form after 13 goals this season.
Inter miss Fredy Guarin, Dodo, Jonathan and Nemanja Vidic, but Hernanes returns from suspension.
The Nerazzurri wasted so many golden opportunities to close on the European places this season, including last week’s 2-1 home defeat to a second string Juventus.
Genoa: Perin; Roncaglia, Burdisso, De Maio; Rincon, Tino Costa, Kucka, Edenilson; Bertolacci, Pavoletti, Iago Falque
Genoa bench: Lamanna, Sommariva, Tambè, Izzo, Perotti, Lestienne, Soprano, Panico, Mandragora, Laxalt
Inter: Handanovic; D'Ambrosio, Ranocchia, Juan Jesus, Nagatomo; Kovacic, Medel, Brozovic; Hernanes; Palacio, Icardi
Inter bench: Carrizo, Andreolli, Campagnaro, Kuzmanovic, Obi, Santon, Felipe, Gnoukouri, Puscas, Donkor, Shaqiri, Bonazzoli