Lazio will look to Ciro Immobile against Harry Kane’s Bayern Munich in the first leg of the Champions League Round of 16 at the Stadio Olimpico.
It kicks off at 20:00 GMT in Rome.
The Biancocelesti must cope without the injured Mattia Zaccagni and Nicolò Rovella, but Patric is available on the bench.
Matias Vecino didn’t train with the rest of the team on Tuesday but is still favourite to start in central midfield alongside Matteo Guendouzi and Luis Alberto.
Elseid Hysaj and Adam Marusic are expected to start as full-backs, leaving Manuel Lazzari initially on the bench.
Lazio beat Serie A strugglers Cagliari 3-1 on Saturday, while Bayern Munich lost 3-0 to Bayer Leverkusen in the Bundesliga.
Former Juventus winger Kingsley Coman is not available for the Bavarians and the same is true of Serge Gnabry, Konrad Laimer, Alphonso Davies and Bouna Sarr.
England international Kane will start up front with Jamal Musiala, Thomas Muller and Leroy Sané behind the ex-Tottenham star.
Lazio-Bayern Munich: probable line-ups
Lazio (4-3-3): Provedel; Marusic, Gila, Romagnoli, Hysaj; Guendouzi, Vecino, Luis Alberto; Isaksen, Immobile, F Anderson.
Bayern Munich (4-2-3-1): Neuer; Mazraoui, Upamecano, Kim, Guerreiro; Goretzka, Kimmich; Sané, Muller, Musiala; Kane.