Milan completely transform their starting XI for the trip to troubled Sassuolo, including Samuel Chukwueze, Luka Jovic and Rafael Leao upfront.
It kicks off at the Mapei Stadium at 14.00 UK time (13.00 GMT).
The Rossoneri are still shaken after the 1-0 home defeat to Roma in the Europa League quarter-final and are resting most of their stars to be ready for the second leg next Thursday.
On top of that rotation, Mike Maignan is not in the squad due to a muscular issue, with Tommaso Pobega and Pierre Kalulu injured.
That means Marco Sportiello takes the gloves, with Chukwueze, Jovic and Leao as the all-new trident.
There is no rest for Leao because of his dismal performance against Roma.
Sassuolo are at serious risk of relegation after dropping to penultimate place, although new coach Davide Ballardini stabilised things a little with a win over Frosinone and draws with Udinese and Salernitana.
Domenico Berardi, Marcus Pedersen and former Milan winger Samu Castillejo are on the treatment table.
Sassuolo: Consigli; Toljan, Erlic, Ferrari, Viti; Boloca, Obiang; Volpato, Thorstvedt, Laurienté; Pinamonti
Milan: Sportiello; Florenzi, Kjaer, Thiaw, Theo Hernandez; Musah, Adli; Chukwueze, Loftus-Cheek, Leao; Jovic
Player statistic
| Andrea Pinamonti (Assist: Kristian Thorstvedt) |
 |
4' | ||
| Armand Lauriente | |
10' | ||
| Gian Marco Ferrari |  |
19' | ||
| 20' | |
Rafael Leão (Assist: Yunus Musah) |
| Armand Lauriente (Assist: Grégoire Defrel) |
|
53' | ||
| Ruan Tressoldi | |
57' | ||
| 59' | |
Luka Jovic | ||
| 68' | |
Malick Thiaw | ||
| Andrea Pinamonti | |
69' | ||
| 84' | |
Noah Okafor (Assist: Matteo Gabbia) |
Match statistic
