Juventus have the chance to go nine points clear at the top, but are without Carlos Tevez against plucky Cesena.
It kicks off at the Stadio Dino Manuzzi at 19.45 GMT, click here to follow our LIVEBLOG.
Roma were held to a shock 0-0 draw by bottom of the table Parma today, so Juve can extend their lead to nine points, but also want to avoid another upset in a round full of them.
Juventus have the chance to go nine points clear at the top, but are without Carlos Tevez against plucky Cesena.
It kicks off at the Stadio Dino Manuzzi at 19.45 GMT, click here to follow our LIVEBLOG.
Roma were held to a shock 0-0 draw by bottom of the table Parma today, so Juve can extend their lead to nine points, but also want to avoid another upset in a round full of them.
Top scorer Tevez is suspended, joining injured Alessandro Matri, Kwadwo Asamoah, Martin Caceres and Romulo.
Alvaro Morata therefore partners Fernando Llorente in an all-Spanish strike force.
Cesena beat Lazio here in their last home match, which is played on artificial turf at the Stadio Manuzzi.
It’s a special game for goalkeeper Nicola Leali, who is on loan from Juventus and destined for a future in Turin.
Out of action for the Sea Horses are Guido Marilungo, Luca Valzania, Andrea Tabanelli, Emmanuel Cascione, Riccardo Cazzola and Nico Pulzetti.
Gregoire Defrel is the one to watch in attack, although he is suffering from flu symptoms.
The Sea Horses only won this fixture once in Serie A, back in 1975-76, along with six draws and five defeats.
Cesena: Leali; Perico, Lucchini, Krajnc, Renzetti; Ze Eduardo, De Feudis, Giorgi; Brienza; Defrel, Djuric
Juventus: Buffon; Lichtsteiner, Bonucci, Ogbonna, Evra; Pogba, Pirlo, Marchisio; Vidal; Llorente, Morata