Massimiliano Allegri must cope without Paulo Dybala and Adrien Rabiot for the trip to Russia, while Matthijs de Ligt is back in the Juventus squad.
The coach has picked the squad ahead of the match in the Champions League on Wednesday.
Allegri already confirmed De Ligt will start the game in Russia, with Wojciech Szczesny and Leonardo Bonucci the two other certainties in the formation.
It’s a thin attack heading to St Petersburg, with Alvaro Morata and Moise Kean the only two strikers on the list, while Adrien Rabiot is still out with coronavirus.
Arthur Melo returned against Roma and is included in the squad travelling for the third match in the European cup.
Juventus squad to face Zenit:
Goalkeepers: Szczesny, Pinsoglio, Perin
Defenders: De Sciglio, Chiellini, De Ligt, Danilo, Cuadrado, Alex Sandro, Bonucci, Rugani
Midfielders: Arthur, Ramsey, McKennie, Bernardeschi, Chiesa, Locatelli, Bentancur, Kulusevski
Attackers: Morata, Kean