Juventus have confirmed three of the starting XI for the Coppa Italia Final, while Inter have doubts in attack and defence.
It kicks off at the Stadio Olimpico in Rome on Wednesday at 20.00 UK time (19.00 GMT).
The trophy will be assigned after 90 minutes, or if the scores are level going through extra time and perhaps even penalties.
During his press conference, Juve coach Max Allegri confirmed that Mattia Perin would start in goal, as he has done throughout the competition, with Giorgio Chiellini and Paulo Dybala also in the XI.
Manuel Locatelli, Danilo and Luca Pellegrini are available again after recovering from injury, but Mattia De Sciglio is suspended.
Long-term absentees Weston McKennie, Federico Chiesa and Kaio Jorge have made the trip to Rome anyway to be part of the event.
Juan Cuadrado and Federico Bernardeschi are expected to take the wide roles with Denis Zakaria and Adrien Rabiot in the middle, supporting Dybala and Dusan Vlahovic.
It remains to be seen whether this is a 4-4-2 or a 3-5-2, as it includes players who can adapt to various roles.
Inter have almost a full squad at their disposal, as Matias Vecino pulled out in training, while Alessandro Bastoni needs a fitness test, as he has been out for several weeks.
Unlike Juve, the Nerazzurri have kept using Samir Handanovic for all but one of their Coppa Italia matches this season.
The only real concerns are upfront, although Edin Dzeko and Lautaro Martinez ought to be the front pairing, with Alexis Sanchez and Joaquin Correa ready to come off the bench.
Inter (3-5-2): Handanovic; Skriniar, De Vrij, Bastoni; Dumfries, Barella, Brozovic, Calhanoglu, Perisic; Lautaro Martinez, Dzeko
Juventus (4-4-2): Perin; Danilo, De Ligt, Chiellini, Alex Sandro; Cuadrado, Zakaria, Rabiot, Bernardeschi; Dybala, Vlahovic