Igor Tudor makes his debut on the Hellas Verona bench and aims to stop Roma maintaining their perfect start to the season, with Tammy Abraham and Nicolò Zaniolo.
It kicks off at the Stadio Bentegodi at 17.00 UK time (16.00 GMT).
Hellas sacked coach Eusebio Di Francesco after three defeats out of three in the League, bringing in former Udinese boss Tudor, who spent last season as assistant manager to Andrea Pirlo at Juventus.
Miguel Veloso, Bosko Sutalo, Kevin Ruegg and Gianluca Frabotta are out of action, while Giovanni Simeone is supported by Daniel Bessa and Gianluca Caprari.
Roma have won all six games played under Jose Mourinho between Serie A and the Europa Conference League.
Matias Vina is on the treatment table with Leonardo Spinazzola, while Henrikh Mkhitaryan is carrying a muscular issue too.
That means Riccardo Calafiori steps in at left-back, with Zaniolo, Lorenzo Pellegrini and Eldor Shomurodov supporting centre-forward Abraham.
Verona: Montipò; Dawidowicz, Gunter, Ceccherini; Faraoni, Barak, Ilic, Lazovic; Bessa, Caprari; Simeone
Roma: Rui Patricio; Karsdorp, Mancini, Ibanez, Calafiori; Cristante, Veretout; Zaniolo, Pellegrini, Shomurodov; Abraham