Stefano Pioli will stick to a three-man defence against Torino tonight, while Nikola Vlasic could play in central midfield for the Granata.
Serie A round 22 begins on Friday night at San Siro. It kicks off at 19.45 UK time.
Pioli must cope without Mike Maignan, Fikayo Tomori, Alessandro Florenzi and Ismael Bennacer, but Zlatan Ibrahimovic is back although the Swede will start on the bench.
The Rossoneri will play with a 3-4-3 formation with Rafael Leao, Olivier Giroud and Brahim Diaz in a front-three.
The Rossoneri are unbeaten in the last 26 home games against Torino in Serie A.
Torino boss Ivan Juric is dealing with an injury crisis in midfield with Ivan Ilic not fully fit and Samele Ricci out of action.
Therefore, Nikola Vlasic should play in central midfield with either Karol Linetty or Michel Adopo taking the other spot in the middle of the park.
David Zima, Pietro Pellegri and Valentino Lazaro are also not available, while Nemanja Radonjic is in doubt.
Alessandro Buongiorno is favourite over Ricardo Rodriguez in defence.
The Granata are unbeaten against Milan this season having picked up a 0-0 draw in the reverse fixture at the Stadio Grande Torino, beating the Rossoneri at San Siro in the Coppa Italia Round of 16 last month.
Milan-Torino: probable line-ups
Milan (3-4-3): Tatarusanu; Thiaw, Kjaer, Kalulu; Saelemaekers, Tonali, Krunic, Theo; Diaz, Giroud, Leao.
Torino (3-4-2-1): Milinkovic-Savic; Djidji, Schuurs, Rodriguez; Aina, Vieira, Linetty, Vojvoda; Miranchuck, Vlasic; Sanabria.