Victor Osimhen and Lorenzo Insigne return for Napoli, but Kalidou Koulibaly is suspended against giant-killers Hellas Verona and Giovanni Simeone.
It kicks off at the Stadio Diego Armando Maradona at 17.00 GMT.
The Partenopei could break away at the top of the table this weekend, as Milan and Inter go head-to-head in the Derby della Madonnina this evening.
The good news for coach Luciano Spalletti is that Osimhen and Insigne are back in the starting XI after minor injuries, while Fabian Ruiz also returns following Thursday’s 4-1 Europa League win over Legia Warsaw.
Koulibaly sits out a ban, with Kostas Manolas, Faouzi Ghoulam and Kevin Malcuit injured, so Juan Jesus has to step into the back four.
Verona have really been transformed since Igor Tudor took over from sacked Eusebio Di Francesco, getting victories over Roma, Lazio and Juventus, while leading 2-0 at Milan before capitulating 3-2.
Giovanni Simeone is on stunning form, putting four past Lazio and another brace against Juve.
He is supported by Antonin Barak and Gianluca Caprari, but Darko Lazovic, Ivica Ilic and Gianluca Frabotta are injured.
Napoli know all too well they cannot take Verona for granted, as a draw here last season cost them a Champions League spot in the final round.
The hosts will be wearing a special edition jersey to mark a year on from Maradona’s death.
Napoli: Ospina; Di Lorenzo, Rrahmani, Juan Jesus, Mario Rui; Anguissa, Fabian Ruiz, Zielinski; Politano, Osimhen, Insigne
Verona: Montipò; Dawidowicz, Gunter, Ceccherini; Faraoni, Tameze, Veloso, Casale; Barak, Caprari; Simeone