Jose Mourinho is back on the Roma bench, but is forced to reshuffle his line-up for this trip to unpredictable Udinese.
It kicks off at the Dacia Arena at 17.00 GMT.
Serie A Liveblog: Including Verona-Napoli, Udinese-Roma and Torino-Inter
Mourinho has completed his two-match Serie A touchline ban, so is back on the bench this evening.
However, Henrikh Mkhitaryan and Marash Kumbulla are suspended, with Leonardo Spinazzola still recovering from Achilles tendon surgery.
Lorenzo Pellegrini steps in behind Nicolò Zaniolo and Tammy Abraham, with Chris Smalling in defence.
Udinese are fresh from a much-needed victory over Sampdoria, but Walace sits out a ban, with Isaac Success carrying a knock.
Beto leads the attack with support from Gerard Deulofeu and Roberto Pereyra.
Udinese: Silvestri; Becao, Pablo Marì, Perez; Molina, Pereyra, Jajalo, Makengo, Udogie; Deulofeu, Beto
Roma: Rui Patricio; Mancini, Smalling, Ibanez; Karsdorp, Cristante, Oliveira, Zalewski; Pellegrini; Zaniolo, Abraham