Edin Dzeko seems favourite to start over Romelu Lukaku in Inter-Lecce at San Siro today, while Samuel Umtiti is back for the Giallorossi.
It kicks off at 17.00 GMT.
Inter must cope without Milan Skriniar and Federico Dimarco as well as Joaquin Correa.
Dzeko is favourite to start in attack with Lautaro Martinez, so Lukaku would initially go on the bench.
With Skriniar injured, Matteo Darmian would start in a three-man defence along with Francesco Acerbi and Alessandro Bastoni.
Inter lost just one of the last 13 Serie A games against Lecce, winning the last eight home meetings in a row.
Lecce defender Federico Baschirotto is serving a one-match ban, but Umtiti is back and will start alongside Alessandro Tuia in defence.
Kastriot Dermaku and Marin Pongračić are also not available for Lecce.
Milan loanee Lorenzo Colombo hasn’t scored or assisted in almost two months and is expected to start on the bench with Assan Ceesay getting the nod up front.
Inter vs. Lecce – probable line-ups
Inter (3-5-2): Onana; Darmian, Acerbi, Bastoni; Dumfries, Barella, Brozovic, Calhanoglu, Gosens; Dzeko, Lautaro Martinez.
Lecce (4-3-3): Falcone; Gendrey, Tuia, Umtiti, Gallo; Gonzalez, Hjulmand, Blin; Strefezza, Ceesay, Di Francesco.