Inter are not sure of Champions League football yet, but look to Lautaro Martinez and Radja Nainggolan in this trip to Napoli.
It kicks off at the Stadio San Paolo at 19.30 UK time (18.30 GMT).
You can follow all the action as it happens from this game and Juventus v Atalanta on the LIVEBLOG.
The Nerazzurri can’t really relax, as they are only one point clear of Atalanta and Milan remain in the running for a top four finish.
Inter are not sure of Champions League football yet, but look to Lautaro Martinez and Radja Nainggolan in this trip to Napoli.
It kicks off at the Stadio San Paolo at 19.30 UK time (18.30 GMT).
You can follow all the action as it happens from this game and Juventus v Atalanta on the LIVEBLOG.
The Nerazzurri can’t really relax, as they are only one point clear of Atalanta and Milan remain in the running for a top four finish.
Above all, Inter’s final game of the season is against an Empoli side that crushed Torino 4-1 today and needs a win to be sure of safety.
Stefan de Vrij is still out injured, so Joao Miranda steps in to central defence, but Danilo D’Ambrosio and Marcelo Brozovic return from suspension.
Coach Luciano Spalletti drops Mauro Icardi, but Matteo Politano can start despite not being 100 per cent fit, with Ivan Perisic, Radja Nainggolan and Lautaro Martinez.
Napoli already have second place locked down, but are always fired up against Inter, especially after their extremely ill-tempered defeat at San Siro in December.
Because of everything that surrounded that match, including the death of an Inter-affiliated ultra during an ambush attempt on travelling Napoli fans, the Nerazzurri supporters have not been sold tickets for this game.
Lorenzo Insigne is back in the squad after injury, but only fit for the bench, so Dries Mertens partners Arkadiusz Milik.
Adam Ounas, Vlad Chiriches, Amadou Diawara and David Ospina are unavailable.
Inter have not conquered Napoli at the San Paolo in Serie A since 1997.
Napoli: Karnezis; Malcuit, Albiol, Koulibaly, Ghoulam; Callejon, Allan, Fabian Ruiz, Zielinski; Mertens, Milik
Inter: Handanovic; D’Ambrosio, Miranda, Skriniar, Asamoah; Gagliardini, Brozovic; Politano, Nainggolan, Perisic; Lautaro Martinez
Ref: Doveri