It’s Carlos Tevez and Andrea Pirlo against Felipe Anderson and Miroslav Klose as leaders Juventus host second placed Lazio.
It kicks off at 19.45 UK time (18.45 GMT), click here to follow our LIVEBLOG.
Juve are runaway leaders at the top of the table, while the Aquile finally leapfrogged Roma into second last week thanks to their eighth consecutive victory.
If Lazio win tonight, it would close the gap at the top to a not-impossible nine points.
It’s Carlos Tevez and Andrea Pirlo against Felipe Anderson and Miroslav Klose as leaders Juventus host second placed Lazio.
It kicks off at 19.45 UK time (18.45 GMT), click here to follow our LIVEBLOG.
Juve are runaway leaders at the top of the table, while the Aquile finally leapfrogged Roma into second last week thanks to their eighth consecutive victory.
If Lazio win tonight, it would close the gap at the top to a not-impossible nine points.
Max Allegri already realised last week that the Champions League quarter-final against Monaco is a big distraction, as they lost 1-0 to bottom of the table Parma.
That was only their second Serie A loss of the campaign, though they are still unbeaten in Turin.
Paul Pogba, Martin Caceres, Kwadwo Asamoah and Romulo are still out of action, joined by the suspended Angelo Ogbonna.
Andrea Barzagli returns from injury and Pirlo starts to get some playing time in his legs, having made his comeback after six weeks against Monaco.
Alessandro Matri gets the nod in attack alongside Tevez, resting Alvaro Morata for the trip to Monaco next Wednesday.
Other than that, it’s a pretty strong starting XI in an apparent 3-5-2 formation.
Lazio are unstoppable at the moment, winning eight on the bounce and reaching the Coppa Italia Final – where they will face Juventus in June.
Federico Marchetti is available with a protective mask after fracturing his nose in training.
Pedro Luis Cavanda and Diego Novaretti sit out bans with Stefan de Vrij, Marco Parolo, Stefan Radu, Filip Djordjevic, Abdoulay Konko and Santiago Gentiletti sidelined.
Felipe Anderson is the pacey Brazilian forward inspiring Lazio, joined by veterans Klose and Stefano Mauri, but Antonio Candreva is benched.
Lorik Cana steps into central defence to fill in for De Vrij, who could be a very big loss indeed for Coach Stefano Pioli.
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Padoin, Vidal, Pirlo, Marchisio, Evra; Tevez, Matri. All. Allegri
Juventus bench: Storari, Rubinho, De Ceglie, Lichtsteiner, Vitale, Sturaro, Marrone, Pereyra, Pepe, Morata, Coman, Llorente
Lazio: Marchetti; Basta, Cana, Mauricio, Braafheid; Cataldi, Biglia, Lulic; Felipe Anderson, Klose, Mauri
Lazio bench: Berisha, Strakosha, Ciani, Pereirinha, Ederson, Ledesma, Onazi, Candreva, Keita, Perea