Gervinho and Mohamed Salah make the trip to Napoli, but Roma miss Francesco Totti and Vasilis Torosidis.
It kicks off on Sunday at 17.00 GMT, click here for a match preview.
Salah made his comeback from an ankle injury in Wednesday’s 0-0 draw with BATE Borisov.
Gervinho’s return from a muscular problem lasted only 25 minutes against Bologna, then he pulled out during the warm-up of that Champions League fixture.
Gervinho and Mohamed Salah make the trip to Napoli, but Roma miss Francesco Totti and Vasilis Torosidis.
It kicks off on Sunday at 17.00 GMT, click here for a match preview.
Salah made his comeback from an ankle injury in Wednesday’s 0-0 draw with BATE Borisov.
Gervinho’s return from a muscular problem lasted only 25 minutes against Bologna, then he pulled out during the warm-up of that Champions League fixture.
Totti, Torosidis and Kevin Strootman are still on the treatment table.
Roma squad for Napoli: Lobont, Rudiger, Digne, Nainggolan, Castan, Iturbe, Dzeko, Salah, Maicon, Falque, Pjanic, De Rossi, Keita, Vainqueur, Gyomber, Florenzi, Szczesny, De Sanctis, Gervinho, Emerson, Manolas, Ucan, Di Livio, D’Urso, Sadiq