Atalanta field a full-strength side in their Coppa Italia Round of 16 clash with Venezia, including Luis Muriel, Matteo Pessina and Teun Koopmeiners.
It kicks off at the Gewiss Stadium in Bergamo at 16.30 GMT.
The tie will be decided after 90 minutes, extra time or even penalties, but away goals are irrelevant in this one-legged fixture.
The winners will go on to face Fiorentina or Napoli in the quarter-final next month.
Atalanta: Musso; Scalvini, Demiral, Palomino; Hateboer, Freuler, Koopmeiners, Pezzella; Pessina, Miranchuk; Muriel
Venezia: Lezzerini; Molinaro, Caldara, Svoboda, Tessmann, Fiordilino, Johnsen, Kiyine, Crnigoj, Ampadu, Okereke