Paulo Dybala is only fit for the bench as Roma welcome Milan this evening, having sprained his ankle in the defeat to Atalanta.
It kicks off at the Stadio Olimpico at 17.00 UK time (16.00 GMT).
The Giallorossi are missing Gini Wijnaldum, Chris Smalling, Diego Llorente and Rick Karsdorp, while Dybala has recovered sufficiently to have a spot on the bench.
Jose Mourinho will have to think carefully before risking La Joya, as he badly sprained his left ankle following a crunching tackle from Atalanta defender Jose Luis Palomino on Monday evening.
It left the Argentina international barely able to put his foot down for the remaining minutes of the match and there were fears of ligament damage.
The tests proved reassuring and Dybala has been given the all-clear to sit on the bench, hoping to perhaps make a late appearance this evening in this showdown for fourth place.