Fiorentina rely on Nico Gonzalez, Lucas Beltran and Andrea Belotti to break down rock solid Viktoria Plzen in the Conference League quarter-final.
The first leg kicks off at the Doosan Arena at 17.45 UK time (16.45 GMT).
You can follow all the build-up and action as it happens from this game, Milan–Roma and Liverpool-Atalanta on the LIVEBLOG.
The Viola reached the Conference League Final last season, losing in nearby Prague to West Ham United, and are eager to go one better this time around.
However, they are up against a Viktoria Plzen side that won all six group games, is still unbeaten in the tournament this season and has not conceded a single goal on home turf.
Vincenzo Italiano has a full squad to choose from and picks Belotti to lead the attack with support from Nico Gonzalez, Beltran and Riccardo Sottil.
Jack Bonaventura is in the stands, having sustained a knock against Juventus.
Viktoria Plzen have several long-term injury absentees, Rafiu Durosinmi, Matej Valenta, Erik Jirka, Jhon Mosquera and now also Jan Sykora, who had knee surgery this week.
Jan Kopic and Sampson Dweh also sit out bans.
Centre-forward Tomas Chory is hard to miss, standing at 1.99 metres tall (over 6ft 6in), but the real danger is Pavel Sulc with 18 goals and five assists in 38 competitive games this season.
Plzen beat Servette on penalties in the Round of 16 after a pair of 0-0 draws and kept six consecutive clean sheets in Europe.
Viktoria Plzen: Jedlicka; Hranac, Hejda, Jemelka; Reznik, Cerv, Kalvach, Cadu; Sulc; Chory, Vydra
Viktoria Plzen bench: Tvrdon, Paluska, Kliment, Traore, Demi, Doubek, Lorincz
Fiorentina: Terracciano; Dodo, Milenkovic, Martinez-Quarta, Biraghi; Arthur, Mandragora; Nico Gonzalez, Beltran, Sottil; Belotti
Fiorentina bench: Christensen, Maxime Lopez, Ikone, Ranieri, Nzola, Infantino, Faraoni, Duncan, Kayode, Parisi, Barak, Kouame
Ref: Grinfeeld (ISR)