Atalanta injury problems continue to pile up, as Ademola Lookman, Lazar Samardzic and Charles De Ketelaere start in the Champions League clash with Shakhtar Donetsk.
It kicks off on neutral turf at the Veltins Arena in Gelsenkirchen at 17.45 UK time (16.45 GMT).
You can follow all the build-up and action as it happens from this game, RB Leipzig-Juventus and Liverpool-Bologna on the Liveblog.
La Dea have stuttered so far this season with a much-changed squad, but earned a more than positive 0-0 home draw with Arsenal in the opening game.
Marco Brescianini and Matteo Ruggeri have joined the absentee list with Isak Hien, Rafael Toloi, Giorgio Scalvini and Gianluca Scamacca.
Davide Zappacosta therefore takes over the left flank, with Raoul Bellanova on the right, but the surprise is that Mateo Retegui remains on the bench, so De Ketelaere becomes a False 9 flanked by Lookman and Samardzic.
Shakhtar Donetsk also played a 0-0 draw in the Champions League, away to Bologna at the Stadio Dall’Ara where Lukasz Skorupski parried an early Georgiy Sudakov penalty.
Danylo Sikan went off injured in that game and is still out along with long-term absentee Tymur Puznakov, but there are suggestions they have changed shape to counter Atalanta’s three-man defence.
Shakhtar Donetsk vs. Atalanta line-ups
Shakhtar Donetsk: Riznyk; Bondar, Ghram, Matviyenko; Gomes, Kryskiv, Stepanenko, Pedro Henrique; Sudakov; Zubkov, Eguinaldo
Atalanta: Carnesecchi; Kossounou, Djimsiti, Kolasinac; Bellanova, De Roon, Ederson, Zappacosta; Samardzic, De Ketelaere, Lookman
Ref: Joao Pinheiro (POR)
Player statistic
| Alaa Ghram |  |
20' | ||
| 21' |  |
Berat Djimsiti (Assist: Ademola Lookman) | ||
| 44' | |
Ademola Lookman (Assist: Sead Kolasinac) |
