Sandro Tonali and Giorgio Scalvini start for Italy in the Under-21 European Championship opener against Pierre Kalulu and Khephren Thuram’s France.
It kicks off at the Cluj Arena at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens on the LIVEBLOG.
Roberto Mancini left Milan midfielder – and soon to be Newcastle United signing – Tonali and Atalanta defender Scalvini to the Azzurrini for this tournament, which is held in Georgia and Romania.
The Under-20 team reached the World Cup Final, losing to Uruguay, and the Azzurrini are hoping to win this competition for a record sixth time, albeit the first since 2004.
Coach Paolo Nicolato has been experimenting with a 3-5-2 formation recently and sticks to that here, largely as so many of the players use this formation at club level.
Raoul Bellanova and Destiny Udogie take the wings, with Pietro Pellegri and Nicolo Cambiaghi upfront, leaving Wilfried Gnonto initially on the bench.
France have several stars at their disposal, including Milan defender Kalulu and OGC Nice midfielder Khephren Thuram, the son of Lilian and brother to Milan target Marcus.
A big name is Olympique Lyonnais midfielder and Under-21 captain Maxence Caqueret.
Italy defeated France in the semi-finals of this competition in both 1994 and 1996.
France U21: Chevalier; Kalulu, Badé, Lukeba, Nkounkou; Koné, Caqueret, K Thuram; Barcola, Kalimuendo; Gouiri
France bench: Meslier, Bajic, Simakan, Larouci, Le Free, Cherki, Gendrey, Chotard, Adli, Diakite, Wahi, Olise
Italy U21: Carnesecchi; Okoli, Pirola, Scalvini; Bellanova, Rovella, Ricci, Tonali, Udogie; Cambiaghi, Pellegri
Italy bench: Caprile, Turati, Parisi, Lovato, Esposito, Colombo, Cittadini, Bove, Gnonto, Cancellieri, Cambiaso, Miretti
Ref: Lindhout (NED)