If Inter win the Champions League against Manchester City, they will set a new all-time record, but there is also an intriguing statistics that unites Lautaro Martinez’s Argentina with this Final.
It kicks off at the Ataturk Stadium in Istanbul at 20.00 UK time (19.00 GMT).
You can follow all the build-up as it happens on the LIVEBLOG.
The Nerazzurri have lost only two games in the competition this season, both in the group stage against Bayern Munich.
That includes the very first fixture, so if Inter go on to win, they will be the first team to lift the Champions League trophy despite losing the opening match.
Curiously, that would mirror the way Lautaro Martinez and Argentina won the World Cup in December, having lost the debut with Saudi Arabia.
Another interesting statistical anomaly is that Manchester City are on the verge of completing the Treble after the Premier League and FA Cup.
In all three previous occasions when Inter won the European Cup, it prevented an opponent from doing the Treble.
They frustrated Real Madrid in 1964, Benfica in 1965 and Bayern Munich by completing their own Treble in 2010.