We begin with Torino-Empoli at 17.30 UK time.
Torino have won the last three home games in a row, but the Tuscans have four victories from six away from the Castellani.
Ivan Juric must do without the injured Andrea Belotti and Koffi Djidji who will be replaced by Antonio Sanabria and David Zima.
Only Szymon Zurkowski is not fully fit for Empoli, so Leo Stulac or Filippo Bandinelli will replace him, with the Italian likely to get the nod.
Lazio-Udinese kicks off at 19.45 UK time.
Udinese travel to the Stadio Olimpico without the injured Roberto Pereyra, while Lazio have Felipe Luiz suspended.
Patric will be deployed at centre-back in place of Felipe Luiz, with Manuel Lazzari starting at right-back.
Lucas Leiva is the favourite to start over Danilo Cataldi in the middle of the park, same as Luis Alberto over Toma Basic.
Torino vs. Empoli
Torino (3-4-2-1): Milinkovic-Savic; Zima, Bremer, Izzo; Aina, Pobega, Lukic, Vojvoda; Praet, Brekalo; Sanabria.
Empoli (4-3-1-2): Vicario; Stojanovic, Tonelli, Luperto, Parisi; Bandinelli, Ricci, Henderson; Di Francesco; Pinamonti, Cutrone.
Lazio vs. Udinese
Lazio (4-3-3): Reina; Lazzari, Patric, Acerbi, Hysaj; Milinkovic, Lucas Leiva, Luis Alberto; Felipe Anderson, Immobile, Pedro.
Udinese (3-4-2-1): Silvestri; Becao, Samir, Nuytinck; Molina, Arslan, Walace, Udogie; Pussetto, Deulofeu; Beto.