Juventus are still coping with injuries, so Massimiliano Allegri will rely on youngsters Matias Soulé, Fabio Miretti and Nicolò Fagioli against Cremonese.
It kicks off at 17.30 GMT.
Cremonese are the only team with no victories in Serie A this term.
Santiago Ascacíbar and Vlad Chiriches are injured. Cremonese have never won against Juventus in history, collecting four draws in 14 meetings. Nevertheless, they kept a clean sheet in each of their last two home games.
Juventus must cope without Mattia De Sciglio, Leonardo Bonucci, Juan Cuadrado, Paul Pogba, Angel Di Maria and Dusan Vlahovic.
Federico Chiesa is available, but not expected to start. Arek Milik will be the only striker and product of Juventus’ academy Fabio Miretti will play behind him in a 3-5-1-1 line-up.
Matias Soulé will likely get the nod on the right flank with Weston McKennie, Fagioli and Manuel Locatelli in the middle of the park.
The Old Lady won without conceding all their last six league matches and haven’t won seven in a row without conceding since March 2018. Juventus secured three consecutive 1-0 victories in their last three away games in Serie A.
Cremonese-Juventus: probable line-ups
Cremonese (4-3-1-2): Carnesecchi, Sernicola, Bianchetti, Hendry, Valeri; Pickel, Castagnetti, Meite; Buonaiuto; Okereke, Dessers
Juventus (3-5-1-1): Szczesny; Danilo, Bremer, Alex Sandro; Soulé, Fagioli, Locatelli, McKennie, Kostic; Miretti; Milik.