Another Liguria derby for Spezia, who host Genoa after a defeat to Sampdoria last Friday.
Thiago Motta’s men won the last home game against Salernitana but have only won two home games on the bounce once in Serie A.
Genoa have three points from their last six days, when both coaches are fighting to keep their jobs in Liguria.
Motta hopes to recover some of the players from the long list of absentees ahead of another crucial derby.
Genoa coach Davide Ballardini is getting used to living an uncertain life at Marassi and should have Bani back in action against Spezia.
Mattia Destro should continue up front, ahead of Goran Pandev, while Felipe Caicedo seems set to start on the bench again.
Form Guide: Spezia (L L L W L) Genoa (D D L D L)
Stat fact: The two teams have only met twice in Serie A and Genoa have picked up two wins against the Aquilotti.
Probable line-ups
Spezia (4-2-3-1): Provedel; Ferrer, Hristov, Nikolaou, Bastoni; Maggiore, Kovalenko; Gyasi, Strelec, Verde; Salcedo
Suspended: none
Injured: Leo Sena, Colley, Agudelo, Erlic, Sala, Bourabia, Kiwior, Reca, Amian, Nguimba
On a yellow card: Nikolaou
Genoa (4-2-3-1): Sirigu; Ghiglione, Vasquez, Biraschi, Criscito; Rovella, Badelj; Kallon, Pandev, Fares; Destro
Suspended: none
Injured: Vanheusden, Maksimovic, Bani, Hernani
On a yellow card: none