Napoli may have a perfect Serie A record, but they suffered their first defeat in the Europa League on Thursday and face a difficult trip to Fiorentina.

The Partenopei won six out of six domestically, but fatigue and the relative lack of squad rotation is beginning to show. Mario Rui saw red in the 3-2 defeat to Spartak Moscow on Thursday evening, while Victor Osimhen and Andre-Frank Zambo Anguissa only rested for one half of a tense and ill-tempered encounter.

Nico Gonzalez returns from suspension for Fiorentina, whose performances have not entirely been met by the results they deserved. Gaetano Castrovilli is still out of action and Jose Callejon should face his former club.

Form Guide: Fiorentina (W L W W W) Napoli (W W W W W)

Stat fact: Dusan Vlahovic could become the first Fiorentina player to score five goals in the first seven games of the Serie A season since Giuseppe Rossi in 2013-14.

Probable line-ups

Fiorentina (4-3-3): Dragowski; Odriozola, Milenkovic, Igor, Biraghi; Bonaventura, Pulgar, Duncan; Callejon, Vlahovic, Gonzalez

Suspended: None

Injured: Ghoulam, Lobotka

On a yellow card: None

Napoli (4-3-3): Ospina; Di Lorenzo, Rrahmani, Koulibaly, Mario Rui; Anguissa, Fabian Ruiz, Zielinski; Lozano, Osimhen, Insigne

Suspended: None

Injured: Castrovilli

On a yellow card: None

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