Juventus again look to Alvaro Morata and Paulo Dybala for the trip to Venezia, who have caused more than a few problems for the big clubs lately.
It kicks off at the Stadio Penzo at 17.00 GMT.
The Bianconeri are feeling confident after topping their Champions League group with a midweek win over Malmo, and of course Zenit doing them a favour by holding Chelsea 3-3 in stoppages.
The injury list remains extensive, with Federico Chiesa, Dejan Kulusevski, Weston McKennie, Danilo and Aaron Ramsey unavailable.
Max Allegri also left Arthur Melo out because the Brazilian turned up late to training.
Morata and Dybala therefore lead the way in a 4-2-3-1 formation.
Venezia beat Roma here and were leading Verona 3-0 before capitulating 4-3 in a crazy game last weekend.
David Okereke and Antonio Vacca are injured, with Pietro Ceccaroni suspended after his red card in that match.
Venezia: Romero; Ebuehi, Modolo, Caldara, Haps; Crnigoj, Ampadu, Busio; Aramu; Henry, Johnsen
Juventus: Szczesny; De Sciglio, Bonucci, De Ligt, Pellegrini; Locatelli, Rabiot; Cuadrado, Dybala, Bernardeschi, Morata
GET DYBALA OUT! INJURY AFTER INJURY! SICK OF IT!@!!