Domenico Berardi is still unavailable as Sassuolo aim for a second straight win against Fabio Quagliarella’s Sampdoria.
It kicks off at the Mapei Stadium in Reggio-Emilia at 17.30 UK time (16.30 GMT).
You can follow all the build-up and action as it happens from today’s four Serie A games on the LIVEBLOG.
The Neroverdi made a good debut under new coach Alessio Dionisi, winning 3-2 away to Hellas Verona.
Captain Berardi is left out again, officially due to injury, unofficially because he is trying to leave in the transfer window, with Matheus Henrique, Pedro Obiang and Filippo Romagna also unavailable.
Samp lost 1-0 at home to Milan and saw Manolo Gabbiadini go off with a sprained ankle, joining Ernesto Torregrossa on the treatment table.
Sassuolo: Consigli; Toljan, Chiriches, Ferrari, Rogerio; Lopez, Frattesi; Djuricic, Raspadori, Boga; Caputo
Sampdoria: Audero; Bereszynski, Yoshida, Colley, Augello; Thorsby, Ekdal; Candreva, Damsgaard, Verre; Quagliarella