Inter are already Winter Champions and could break away at the top with Edin Dzeko and Lautaro Martinez upfront, but Nicolò Barella is suspended against Torino.
It kicks off at San Siro at 17.30 GMT, you can follow all the build-up and action as it happens from today’s seven Serie A games on the LIVEBLOG.
The Nerazzurri are already guaranteed their Winter Champions crown after going four points clear of Milan and Napoli with a game to spare, being top at the midway stage of the season.
Barella is suspended, so Arturo Vidal steps in amid reports he could be leaving Inter in the January transfer window, while Lautaro Martinez returns alongside Dzeko.
Joaquin Correa is the only remaining injury case for Simone Inzaghi.
Torino are still missing Andrea Belotti and Simone Verdi, but Dennis Praet is back in the squad after a right thigh problem.
Simone Zaza returns after he was frozen out for disciplinary reasons, although Marco Benassi is still on the naughty step.
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Dumfries, Vidal, Brozovic, Calhanoglu, Perisic; Dzeko, Lautaro Martinez
Torino: Milinkovic-Savic; Buongiorno, Dijdij, Bremer; Singo, Lukic, Pobega, Aina; Brekalo, Pjaca; Sanabria