Atalanta deal with an injury crisis in defence, looking to Duvan Zapata and Josip Ilicic against Udinese’s new hitman Beto.
It kicks off in Bergamo at 11.30 UK time (10.30 GMT).
La Dea are fresh from a dramatic Old Trafford trip in the Champions League, leading 2-0 at half-time only to capitulate 3-2.
They were already missing Rafael Toloi, Berat Djimsiti, Matteo Pessina, Robin Gosens and Hans Hateboer, then lost Merih Demiral – who had scored one of the goals – at half-time too.
Demiral is back in the squad today despite that muscular issue, but only on the bench, while Joakim Maehle has a stomach bug.
Duvan Zapata and Luis Muriel are former Udinese players, while Juan Musso left over the summer for €20m.
Udinese have Roberto Pereyra suspended and Gerard Deulofeu injured, so are forced to change upfront.
Ignacio Pussetto and Nahuel Molina support summer signing Beto, who found the net in his last two Serie A appearances.
Atalanta (3-4-1-2): Musso; De Roon, Palomino, Lovato; Zappacosta, Pasalic, Freuler, Pezzella; Malinovskyi; Ilicic, Zapata
Udinese (3-4-3): Silvestri; Becao, Nuytinck, Samir; Stryger Larsen, Walace, Makengo, Udogie; Molina, Beto, Pussetto