Roma make changes for this tricky Serie A trip to Venezia and give Lucas Gourna-Douath his first start, while Daniel Fila and Kike Perez get their full debuts.
It kicks off at the Stadio Penzo at 11.30 GMT.
The Giallorossi are coming off a midweek 3-1 Coppa Italia quarter-final defeat to Milan at San Siro, so with the decisive Europa League play-off against FC Porto coming up on Thursday, coach Claudio Ranieri has to rotate his squad.
Manu Koné is suspended, while Mats Hummels and Leandro Paredes did not even make the trip to ensure they rest fully.
Paulo Dybala starts, despite reports that he would drop to the bench, and Artem Dovbyk returns to the starting XI with support from Stephan El Shaarawy.
Venezia have also been very busy in the transfer window, above all selling star striker and fan favourite Joel Pohjanpalo to Palermo.
Filip Stankovic and Michael Svoboda are long-term absentees with knee ligament injuries, along with Marin Sverko and Alfred Duncan.
Their form has slightly improved lately, as although they are without a win since December 22, there were draws against Empoli, Parma and Verona, plus only very narrow defeats to Napoli, Inter and Udinese.
Czech Under-21 international Daniel Fila was signed late on deadline day from Slavia Prague and he is thrown straight into the starting XI, while Spanish midfielder Kike Perez gets his full debut.
This will always be a special game for Eusebio Di Francesco, who was both a player and a coach at Roma.
Venezia vs. Roma line-ups
Venezia (3-5-2): Radu; Marcandalli, Idzes, Candé; Zerbin, Kike Perez, Nicolussi Caviglia, Busio, Ellertsson; Yeboah, Fila
Roma (3-4-2-1): Svilar; Celik, Mancini, Ndicka; Rensch, Gourna-Douath, Cristante, Angeliño; Dybala, El Shaarawy; Dovbyk
Player statistic
| 9' |  |
Lucas Gourna-Douath | ||
| Daniel Fila | |
10' | ||
| Fali Candé | |
24' |
| 57' |  |
Paulo Dybala | ||
| 61' | |
Bryan Cristante | ||
| 69' | |
Zeki Celik |
Match statistic
