Napoli are forced to make changes with Jens Lindstrom joining Victor Osimhen upfront, while Fabio Cannavaro’s Udinese look to Lazar Samardzic and Lorenzo Lucca.
It kicks off at the Bluenergy Stadium at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens from this game and Salernitana–Atalanta on the LIVEBLOG.
Other results this weekend really shook up the race to avoid relegation, so a win here would allow Udinese to catch Empoli and Frosinone.
However, there’s a lengthy absentee list for new coach Cannavaro, including suspended Nehuen Perez and Martin Payero.
There are injuries to Florian Thauvin, Sandi Lovric, Lautaro Giannetti, Marco Silvestri, Gerard Deulofeu and Kingsley Ehizibue.
Lucca and former Napoli transfer target Samardzic start with surprise pick Brenner.
Napoli have problems too, as Kvicha Kvaratskhelia and his natural replacement Giacomo Raspadori are both out of action, along with Piotr Zielinski, Giacomo Raspadori and Leander Dendoncker.
Lindstrom therefore gets a rare start in the trident with Osimhen and Matteo Politano.
As this game falls on the anniversary of the devastating Friuli earthquake of May 1976, play will half for a moment at the 21.02 local time to remember the 965 victims of the tragedy.
Udinese vs. Napoli line-ups
Udinese: Okoye; Joao Ferreira, Bijol, Kristensen; Ehizibue, Walace, Zarraga, Kamara; Samardzic, Brenner; Lucca
Napoli: Meret; Di Lorenzo, Rrahmani, Ostigard, Olivera; Anguissa, Lobotka, Cajuste; Politano, Osimhen, Lindstrom
Player statistic
| 51' |  |
Victor Osimhen (Assist: Matteo Politano) | ||
| Isaac Success (Assist: Thomas Kristensen) |
|
90+2' |
Match statistic
