Milan are out for revenge against Udinese with Olivier Giroud, Christian Pulisic and Rafael Leao, plus Yacine Adli in midfield again.
It kicks off at the Bluenergy Stadium at 19.45 GMT.
Stefano Pioli hopes the Rossoneri have found some form now after three consecutive Serie A victories, despite the lengthy absentee list.
Samuel Chukwueze and Ismael Bennacer are on international duty, with Malick Thiaw, Fikayo Tomori, Pierre Kalulu, Tommaso Pobega and Mattia Caldara injured.
Giroud had been in doubt with flu symptoms, but is ready to start with Leao, Pulisic and Ruben Loftus-Cheek in a more advanced role.
Theo Hernandez has returned to left-back after a spell in central defence, while Adli impressed last time out against Roma.
Udinese are a deeply unpredictable team, as they have managed only two victories in Serie A all season, but those were at San Siro against Milan in November and beating high-flying Bologna 3-0 last month.
They are fresh off a 2-2 draw with fourth-placed Fiorentina, a game they had been leading until a late penalty.
Jaka Bijol, Enzo Ebosse, Vivaldo Semedo and Gerard Deulofeu are all long-term absentees, while Simone Pafundi is on the verge of a transfer to FC Lausanne-Sport.
Veteran Roberto Pereyra supports Lorenzo Lucca upfront, but Lazar Samardzic’s future remains uncertain after talks with Napoli and Juventus.
Udinese: Okoye; Ferreira, Perez, Kristensen; Ebosele, Lovric, Walace, Samardzic, Kamara; Pereyra; Lucca
Milan: Maignan; Calabria, Kjaer, Gabbia, Theo Hernandez; Adli, Reijnders; Pulisic, Loftus-Cheek, Leao; Giroud
Player statistic
31' | Ruben Loftus-Cheek (Assist: Theo Hernández) | |||
Lazar Samardžić (Assist: Lorenzo Lucca) |
42' | |||
Hassane Kamara | 45+1' |
Festy Ebosele | 52' | |||
Florian Thauvin | 56' | |||
Florian Thauvin | 62' | |||
Walace | 65' | |||
Lorenzo Lucca | 71' | |||
João Ferreira | 78' | |||
83' | Luka Jovic | |||
88' | Theo Hernández | |||
90+3' | Noah Okafor (Assist: Olivier Giroud) |