Napoli can consolidate third place and again use an all-attack approach with Dries Mertens, Lorenzo Insigne, Hirving Lozano and Victor Osimhen against Andrea Belotti’s Torino.
It kicks off at the Stadio Olimpico Grande Torino at 14.00 UK time (13.00 GMT).
Serie A Liveblog: Torino-Napoli, Sassuolo-Udinese, Lazio-Samp
The Partenopei have already secured a Champions League spot for next season and have the opportunity to break away from Juventus, who were beaten 2-1 by Genoa last night.
Fresh from a 6-1 mauling of Sassuolo, Napoli again use all their forwards simultaneously in a 4-2-3-1 formation, with Stanislav Lobotka back in the squad after injury.
Toro want to stay in the top half of the table, but lose Sasa Lukic to suspension, with Antonio Sanabria and Mohamed Fares out of action.
Belotti starts what may well be one of his final games in the Torino jersey with support from Josip Brekalo and Denis Praet.
Il Gallo scored a hat-trick against Empoli last week, taking him to 100 goals for the Granata, and has been linked with Napoli for next season.
Torino are wearing a special patch on their jerseys as this week was the anniversary of the Superga tragedy, which saw the entire Grande Torino team killed in a plane crash in May 1949.
Torino: Berisha; Izzo, Bremer, Rodriguez; Singo, Ricci, Mandragora, Vojvoda; Praet, Brekalo; Belotti
Napoli: Ospina; Di Lorenzo, Rrahmani, Koulibaly, Mario Rui; Fabian Ruiz, Anguissa; Lozano, Mertens, Insigne; Osimhen