Inter want to recapture the top of the Serie A table and field their best available XI including Lautaro Martinez and Marcus Thuram, while Torino look to Pietro Pellegri.
It kicks off at the Stadio Olimpico Grande Torino at 17.00 UK time (16.00 GMT).
The Nerazzurri went into the break for international duty with a draw against Bologna, which plunged them down to second place behind rivals Milan.
Marko Arnautovic and Juan Cuadrado are still out of action, with Alexis Sanchez returning late from international duty, so it’s Lautaro Martinez and Thuram upfront again.
Despite another goal for Italy, Davide Frattesi is once more on the bench.
Torino have just two points from the last four matches and are without injured Duvan Zapata, Yann Karamoh, Koffi Djidji, Alessandro Buongiorno and Brandon Soppy.
Pellegri is preferred to Antonio Sanabria upfront, with Nikola Vlasic in support.
Torino: Milinkovic-Savic; Tameze, Schuurs, Rodriguez; Bellanova, Ricci, Linetty, Lazaro; Vlasic, Seck; Pellegri
Inter: Sommer; Pavard, De Vrij, Acerbi; Darmian, Barella, Calhanoglu, Mkhitaryan, Dimarco; Thuram, Lautaro Martinez
Player statistic
49' | Nicolò Barella | |||
59' | Marcus Thuram (Assist: Denzel Dumfries) | |||
67' | Lautaro Martínez (Assist: Francesco Acerbi) | |||
Karol Linetty | 80' | |||
90+5' | Hakan Calhanoglu | |||
90+6' | Carlos Augusto |