Inter rely on Romelu Lukaku and Lautaro Martinez upfront, with Marcelo Brozovic and Samir Handanovic back in the starting XI for this trip to M’Bala Nzola’s Spezia.
It kicks off at the Stadio Alberto Picco at 19.45 GMT.
You can follow all the build-up and action as it happens on the LIVEBLOG.
The Nerazzurri have the opportunity to further close the gap on leaders Napoli and keep the chasing pack at bay in the battle for a top four finish.
They are also preparing for Tuesday’s Champions League Round of 16 visit to FC Porto, after winning the first leg 1-0, so Simone Inzaghi is tempted to rotate the squad.
Milan Skriniar and Joaquin Correa are still out of action, while Federico Dimarco is only fit for a spot on the bench.
Brozovic and Handanovic are given rare starts, with Robin Gosens in his third consecutive match.
Lukaku gets the nod ahead of Edin Dzeko to partner Lautaro Martinez.
Spezia are without a win since mid-January, managing three draws and four defeats, and made their debut under new coach Leonardo Semplici with last week’s stalemate against Verona.
Arkadiusz Milik and reserve goalkeeper Federico Marchetti are suspended, with Simone Bastoni, Emil Holm and Joao Moutinho on the treatment table.
Nzola leads the attack, supported by Eldor Shomurodov, Kevin Agudelo and Emanuel Gyasi in a move to a 3-5-2 formation.
Inter have never lost to Spezia in all competition, winning eight of their nine competitive meetings.
Spezia: Dragowski; Ampadu, Caldara, Nikolaou; Amian, Agudelo, Bourabia, Zurkowski, Gyasi; Shomurodov, Nzola
Inter: Handanovic; D’Ambrosio, Acerbi, Bastoni; Darmian, Barella, Brozovic, Mkhitaryan, Gosens; Lukaku, Lautaro Martinez
Player statistic
| Emmanuel Gyasi |  |
6' | ||
| Mattia Caldara | |
12' | ||
| 13' |  |
Lautaro Martínez |
| Daniel Maldini (Assist: M’Bala Nzola) |
 |
55' | ||
| Dimitrios Nikolaou | |
71' | ||
| 83' |  |
Romelu Lukaku | ||
| M’Bala Nzola | |
85' |
Match statistic
