Torino are forced into changes after yet more injuries, while Sassuolo go looking for a fifth Serie A win on the bounce thanks to Domenico Berardi and Armand Laurientè.
It kicks off at the Mapei Stadium at 19.45 UK time (18.45 GMT).
The Neroverdi have won their last four consecutive Serie A matches to climb up the table, sitting one point above the Granata going into this weekend.
Ruan Tressoldi returns, as only Mert Muldur is still out of action, with Davide Frattesi in midfield supporting the trident attack of Berardi, Andrea Pinamonti and Laurientè.
Ivan Juric has yet more injury problems to deal with, as Ivan Ilic and Ola Aina have both been ruled out for about a month.
They join Yann Karamoh, David Zima and Ronaldo Vieira on the treatment table.
Sassuolo: Consigli; Toljan, Ferrari, Ruan, Rogerio; Frattesi, Maxime Lopez, Henrique; Berardi, Pinamonti, Laurientè
Torino: Milinkovic-Savic; Gravillon, Schuurs, Buongiorno; Singo, Ricci, Linetty, Rodriguez; Vlasic, Radonjic; Sanabria
Player statistic
| Andrea Pinamonti |  |
36' |
| 66' | |
Antonio Sanabria (Assist: Valentino Lazaro) | ||
| Davide Frattesi |  |
75' | ||
| 90+5' | |
Karol Linetty |
Match statistic
