Juventus look to Angel Di Maria and Dusan Vlahovic, with Federico Chiesa on the bench, against a Salernitana side with Boulaye Dia, Krzysztof Piatek and Antonio Candreva.
It kicks off at the Stadio Arechi at 19.45 GMT.
You can follow all the build-up and action as it happens on the LIVEBLOG.
Following the 15-point penalty for artificially inflating transfer fees, Juve find themselves only two points above today’s opponents in the table, so Max Allegri warned his men to start treating this like a relegation dogfight.
Arkadiusz Milik, Leonardo Bonucci, Leandro Paredes, Paul Pogba and Kaio Jorge are all still out injured, but Chiesa is dropped to the bench in favour of Vlahovic and Di Maria.
Salernitana are still missing Federico Fazio, Giulio Maggiore, Pasquale Mazzocchi and Norbert Gyomber, but their confidence was boosted by a win away to Lecce last week.
That ended a run of just two points from seven rounds.
January buys Guillermo Ochoa and William Troost-Ekong have already made an impact, with Juventus-owned Hans Nicolussi Caviglia in midfield.
These teams played an extraordinarily controversial 2-2 draw in Turin back in September, when Salernitana were 2-0 up, pegged back to 2-2 and then a last-gasp Arek Milik winner was incorrectly disallowed by VAR.
Candreva was in a blind spot for their cameras, so was not spotted keeping everyone onside.
That is no longer possible now that Semi-Automatic Offside Technology has been brought in.
Salernitana: Ochoa; Sambia, Troost-Ekong, Bronn, Bradaric; Candreva, Coulibaly, Nicolussi Caviglia, Vilhena, Dia; Piatek
Juventus: Szczesny; Danilo, Bremer, Alex Sandro; De Sciglio, Rabiot, Locatelli, Miretti, Kostic; Di Maria; Vlahovic