Ivan Juric makes his debut on the Roma bench, starting Paulo Dybala and Artem Dovbyk with a new system against surprise Serie A leaders Udinese.
It kicks off at the Stadio Olimpico at 17.00 UK time (16.00 GMT).
It has been a shocking few days for the Giallorossi, who suddenly announced the sacking of Daniele De Rossi on Wednesday morning.
Fans were in uproar and are protesting today, leaving the stands of the Curva Sud empty for the first 30 minutes.
There was further chaos this morning with news CEO Lina Souloukou had resigned from her role.
Former Torino boss Juric steps in and immediately transforms the tactics to his traditional three-man defence, but as Mario Hermoso and Mats Hummels are not at 100 per cent, Angelino is in the back three.
He tries to balance Dybala and Lorenzo Pellegrini in support of centre-forward Dovbyk, but Enzo Le Fée and Alexis Saelemaekers are out of action.
A big surprise is Bryan Cristante in midfield rather than summer signing Manu Kone’.
Udinese were the surprise Serie A leaders going into this weekend after an opening draw with Bologna and three victories on the bounce.
Alexis Sanchez is not fully fit yet, so Brenner and Florian Thauvin support Lorenzo Lucca.
Roma vs. Udinese line-ups
Roma: Svilar; Mancini, N’Dicka, Angelino; Celik, Pisilli, Cristante, El Shaarawy; Dybala, Pellegrini; Dovbyk
Udinese: Okoye; Kabasele, Bijol, Kristensen; Ehizibue, Ekkelenkamp, Karlstrom, Kamara; Thauvin, Brenner; Lucca
Player statistic
| 3' |  |
Lorenzo Lucca | ||
| Artem Dovbyk (Assist: Stephan El Shaarawy) |
 |
19' | ||
| Niccolò Pisilli | |
31' | ||
| 39' | |
Thomas Kristensen |
| Paulo Dybala |  |
49' |
