Roma have Paulo Dybala back on the bench, but Cristian Volpato starts with Nicolò Zaniolo and Tammy Abraham against high-flying Torino with Nikola Vlasic and Antonio Sanabria.
It kicks off at the Stadio Olimpico at 14.00 GMT.
The Giallorossi have stuttered recently, including defeats to Napoli and Lazio, then a midweek draw at Sassuolo that sparked controversy with Jose Mourinho’s criticism of Rick Karsdorp.
Inevitably, the Dutchman is dropped and not even on the bench, while Lorenzo Pellegrini, Leonardo Spinazzola and Georginio Wijnaldum are injured.
Dybala wants to prove his World Cup fitness and is back on the bench for the first time since suffering a thigh strain while taking a penalty against Lecce on October 9, but Volpato and Zaniolo support Abraham.
Meanwhile, former Torino hitman Andrea Belotti is ready to face his old teammates.
The Granata are missing Pietro Pellegri, Perr Schuurs, Ola Aina and Sasa Lukic, so Aleksei Miranchuk and Nikola Vlasic support returning centre-forward Antonio Sanabria, sending Nemanja Radonjic to the bench.
Roma: Rui Patricio; Mancini, Smalling, Ibanez; Celik, Camara, Cristante, Zalewski; Volpato, Zaniolo; Abraham
Torino: Milinkovic-Savic; Djidji, Zima, Buongiorno; Lazaro, Linetty, Ricci, Vojvoda; Miranchuk, Vlasic; Sanabria