Paulo Dybala and Romelu Lukaku lead the way against Giacomo Bonaventura and M’Bala Nzola, as Roma and Fiorentina go head-to-head for fourth place, but Nico Gonzalez is not fully fit.
It kicks off at the Stadio Olimpico at 19.45 GMT.
You can follow all the build-up and action as it happens from today’s Serie A games on the LIVEBLOG.
These teams are separated by only one point and whoever wins will take fourth place, while the Giallorossi could close to within two points of Milan in third.
Chris Smalling, Tammy Abraham and Marash Kumbulla are the only remaining absentees, as Jose Mourinho is starting to get almost a full squad to work with.
Lorenzo Pellegrini is preferred to Edoardo Bove and Rasmus Kristensen picked after impressing against Sassuolo.
Fiorentina are without Dodo and Gaetano Castrovilli, while Nico Gonzalez was a major doubt until the last minute.
He is indeed only on the bench to begin with.
The Viola had extra strain after being forced to extra time and a penalty shoot-out by Parma in the Coppa Italia on Wednesday evening.
Jonathan Ikone missed that match with flu symptoms, but is available again, with Nzola preferred to Lucas Beltran.
Roma: Rui Patricio; Mancini, Llorente, Ndicka; Kristensen, Cristante, Paredes, Pellegrini, Zalewski; Dybala, Lukaku
Fiorentina: Terracciano; Kayode, Ranieri, Martinez-Quarta, Biraghi; Arthur, Duncan; Kouame, Bonaventura, Ikone; Nzola
Player statistic
| Romelu Lukaku (Assist: Paulo Dybala) |
 |
5' | ||
| Bryan Cristante |  |
37' | ||
| Nicola Zalewski | |
41' |
| Nicola Zalewski |  |
64' | ||
| 64' | |
Jonathan Ikoné | ||
| 66' | |
Lucas Martínez Quarta (Assist: Christian Kouamé) | ||
| 75' | |
Cristiano Biraghi | ||
| Leandro Paredes | |
80' | ||
| 86' | |
Alfred Duncan | ||
| Romelu Lukaku |  |
87' | ||
| Diego Llorente | |
90+6' |
Match statistic
