Napoli have Kvicha Kvaratskhelia and Giovanni Simeone back along with a return to the 4-3-3 formation against a transformed Verona.
It kicks off at the Stadio Diego Armando Maradona at 14.00 GMT.
The Partenopei are still shaking off the tension from the Supercoppa Italiana Final defeat to Inter, and the goalless trip to Lazio in Serie A.
They had a decimated squad in that match, but Kvaratskhelia and Simeone return from suspension, although Piotr Zielinski joins Alex Meret and Mathias Olivera on the treatment table.
Victor Osimhen is still at the Africa Cup of Nations, where Nigeria qualified for the semi-finals, but Andre Frank Zambo Anguissa is available again.
Cyril Ngonge moved from Verona to Napoli in January and is on the bench, but the big news is the return to a four-man defence after several weeks of three at the back.
Hellas were transformed in the transfer window and are therefore an unknown quantity, signing 10 new players and selling 16.
Only Stefan Mitrovic misses out on the trip.
Napoli: Gollini; Di Lorenzo, Rrahmani, Juan Jesus, Mario Rui; Anguissa, Lobotka, Cajuste; Politano, Simeone, Kvaratskhelia
Verona: Montipó; Tchatchoua, Coppola, Dawidowicz, Cabal; Duda, Serdar; Folorunsho, Suslov, Lazovic; Noslin
Player statistic
33' | Diego Coppola |
Mário Rui | 46' | |||
54' | Tomas Suslov | |||
Jesper Lindström | 66' | |||
72' | Diego Coppola (Assist: Tomas Suslov) | |||
Stanislav Lobotka | 76' | |||
Cyril Ngonge (Assist: Jesper Lindström) |
79' | |||
Khvicha Kvaratskhelia (Assist: Pasquale Mazzocchi) |
87' |