It kicks off at the Stadio Diego Armando Maradona at 19.45 UK time (18.45 GMT).
The Partenopei won the Scudetto last season, but that feels like a lifetime ago, as they are facing multiple fires.
After Kvicha Kvaratskhelia and Osimhen were caught on camera berating Garcia for substitutions, with just two points from three Serie A rounds, another scandal erupted last night.
The official Napoli TikTok account posted a video mocking Osimhen for missing the penalty against Bologna, prompting the striker’s agent to threaten legal action and the player to remove all images of him in the club jersey from his social media.
It is therefore a very tense atmosphere this evening, while Natan again plays in defence because Juan Jesus and Amir Rrahmani are both injured.
Udinese are without a win this season, coming off a 2-0 home defeat to Fiorentina that only highlighted their lack of attacking threat.
Injuries include Enzo Ebosse, Vivaldo Semedo, Daniele Padelli, Christian Kabasele, Brenner, Adam Masina, Gerard Deulofeu, Keinan Davis and Kingsley Ehizibue.
Napoli: Meret; Di Lorenzo, Ostigard, Natan, Mario Rui; Anguissa, Lobotka, Zielinski; Politano, Osimhen, Kvaratskhelia
Udinese: Silvestri; Perez, Bijol, Kristensen; Ebosele, Payero, Walace, Lovric, Kamara; Thauvin, Lucca
(Assist: Matteo Politano)
|81'||Lazar Samardzic |
(Assist: Isaac Success)
(Assist: Khvicha Kvaratskhelia)