Champions of Italy Milan are without Sandro Tonali, while Olivier Giroud is only fit for the bench, so Ante Rebic and Rade Krunic start against Udinese, but Tottenham target Destiny Udogie is not in the squad.
It kicks off at 17.30 UK time (16.30 GMT), you can follow all the action as it happens from today’s four Serie A games on the LIVEBLOG.
The Rossoneri begin the defence of their title at San Siro against Udinese, but are as always forced to do without several players due to injury.
Zlatan Ibrahimovic is a long-term absentee, but Olivier Giroud and Divock Origi are not 100 per cent fit either, so Rebic starts upfront.
Big signing Charles De Ketelaere is on the bench and Krunic steps in for injured Sandro Tonali in midfield.
Udinese under new coach Andrea Sottil have Tolgay Arslan out of action, with centre-forward Beto only ready for the bench, so Gerard Deulofeu and Isaac Success lead the way.
Future Tottenham Hotspur signing Udogie is not even on the bench and will fly out after the game for his Spurs medical, but remain on loan at Udinese for the rest of the season.
Milan: Maignan, Calabria, Kalulu, Tomori, Theo Hernandez; Bennacer, Krunic; Messias, Diaz, Leao; Rebic
Udinese: Silvestri; Becao, Perez, Nuytinck; Soppy, Pereyra, Walace, Makengo, Masina; Deulofeu, Success