Champions of Italy Milan are without Sandro Tonali, while Olivier Giroud is only fit for the bench, so Ante Rebic and Rade Krunic start against Udinese, but Tottenham target Destiny Udogie is not in the squad.
It kicks off at 17.30 UK time (16.30 GMT), you can follow all the action as it happens from today’s four Serie A games on the LIVEBLOG.
The Rossoneri begin the defence of their title at San Siro against Udinese, but are as always forced to do without several players due to injury.
Future Tottenham Hotspur signing Udogie is not even on the bench and will fly out after the game for his Spurs medical, but remain on loan at Udinese for the rest of the season.
Milan: Maignan, Calabria, Kalulu, Tomori, Theo Hernandez; Bennacer, Krunic; Messias, Diaz, Leao; Rebic
Udinese: Silvestri; Becao, Perez, Nuytinck; Soppy, Pereyra, Walace, Makengo, Masina; Deulofeu, Success