Milan could theoretically win the Scudetto this weekend, but Atalanta need a victory for Europa League qualification, so both teams will go all-out attack at San Siro.
It kicks off at 17.00 UK time (16.00 GMT), you can follow all the build-up and action as it happens from today’s four Serie A games on the LIVEBLOG.
Serie A Liveblog: Milan-Atalanta, Cagliari-Inter, Napoli-Genoa, Bologna-Sassuolo
The Rossoneri will be able to celebrate the title with a round to spare if they get a better result than Inter manage in tonight’s trip to Cagliari.
They have a superior head-to-head record with Inter, so if the two rivals finish level at the top, Milan have the upper hand.
Simon Kjaer is the only remaining injury absentee, with Rade Krunic again used in the trequartista role flanked by Alexis Saelemaekers and Rafael Leao, supporting Olivier Giroud.
It is Franck Kessie’s last game at San Siro before his move to Barcelona.
Atalanta have plenty to play for too, as a win would let them leapfrog Roma and at least temporarily catch Lazio in fifth.
They are missing Rafael Toloi, Giuseppe Pezzella and Josip Ilicic, but Merih Demiral returns to the starting XI.
Gian Piero Gasperini has seemingly moved to a 4-3-2-1 formation with Matteo Pessina and Mario Pasalic behind Luis Muriel.
Milan: Maignan; Calabria, Kalulu, Tomori, Theo Hernandez; Tonali, Kessie; Saelemaekers, Krunic, Leao; Giroud
Atalanta: Musso; Djimsiti, De Roon, Palomino, Hateboer; Freuler, Koopmeiners, Zappacosta; Pessina, Pasalic; Muriel