Lazio give Marcos Antonio his first start with Sergej Milinkovic-Savic and Ciro Immobile, as they host Hellas Verona.
It kicks off at the Stadio Olimpico at 17.00 UK time (16.00 GMT).
Danilo Cataldi is suspended and Pedro still nursing that ankle injury, while Luis Alberto is rested following Thursday’s 4-2 Europa League win over Feyenoord.
That means summer signing Marcos Antonio gets his first start, supporting Ciro Immobile, Felipe Anderson and Mattia Zaccagni.
Ex-Verona defender Nicolo’ Casale gets his debut in the Lazio shirt.
Verona are fresh from their first win of the season against Sampdoria, earned by Scottish youngster Josh Doig’s debut goal.
Coach Gabriele Cioffi has a full squad to choose from with Pawel Dawidowicz and Roberto Piccoli available again.
Ivan Ilic was repeatedly linked with Lazio over the summer and he starts for Hellas.
Lazio: Provedel; Lazzari, Patric, Casale, Marusic; Milinkovic-Savic, Marcos Antonio, Basic; Felipe Anderson, Immobile, Zaccagni
Verona: Montipò; Ceccherini, Hien, Coppola; Terracciano, Ilic, Veloso, Doig, Lazovic; Lasagna, Henry