The Juventus injury crisis keeps growing, so Max Allegri gives Moise Kean a chance against Salernitana’s on-form hitman Boulaye Dia and new buy Krzysztof Piatek.
It kicks off at the Allianz Juventus Stadium in Turin at 19.45 UK time (18.45 GMT).
The Bianconeri are still struggling for consistency this season, drawing three of their opening five Serie A games, including the most recent trip to Fiorentina.
They were also beaten 2-1 by PSG in the Champions League midweek and the latest additions to the injury list are Manuel Locatelli and Adrien Rabiot.
They join Angel Di Maria, Paul Pogba, Wojciech Szczesny, Federico Chiesa and Kaio Jorge, so Max Allegri gives Kean a chance to shine.
Salernitana are unbeaten in four, having crushed Sampdoria 4-0 among draws against Udinese, Bologna and Empoli.
Boulaye Dia is on stunning form, the ex-Villarreal striker contributing three goals and two assists in just four Serie A games.
Franck Ribery, Ivan Radovanovic, Emil Bohinen and Matteo Lovato are injured, with deadline day signing Krzysztof Piatek getting his first start.
Juventus: Perin; Cuadrado, Bremer, Bonucci, De Sciglio; McKennie, Paredes, Miretti, Kostic; Kean, Vlahovic
Salernitana: Sepe; Bronn, Fazio, Daniliuc; Candreva, Coulibaly, Maggiore, Vilhena, Mazzocchi; Piatek, Dia