Fiorentina and Roma go head-to-head for the opportunity to close on fourth place, as Andrea Belotti faces his former club with Nico Gonzalez against Romelu Lukaku and Paulo Dybala.
It kicks off at the Stadio Artemio Franchi at 19.45 GMT.
You can follow all the build-up and action as it happens from today’s Serie A games on the LIVEBLOG.
Both teams were involved in Europe on Thursday, as the Viola won 4-3 over Maccabi Haifa in Budapest, while the Giallorossi crushed Brighton and Hove Albion 4-0.
Lucas Beltran is suspended, with Christian Kouame still recovering after contracting malaria at AFCON, but Lucas Martinez-Quarta and Arthur Melo return to the squad.
It is a special occasion for Belotti, who left Roma in January to join Fiorentina on loan and is eager to show what he can do.
Rasmus Kristensen sits out a ban, with Tammy Abraham the only remaining injury absentee, as Daniele De Rossi has transformed this team.
Since taking over from Jose Mourinho on January 16, the coach has overseen eight wins, one draw and a defeat to Inter in all competition.
Dybala, Lukaku and Stephan El Shaarawy complete the trident attack, with Angelino stepping in for Leonardo Spinazzola.
Houssem Aouar gets a rare start, as Lorenzo Pellegrini needs rest.
Fiorentina: Terracciano; Kayode, Milenkovic, Ranieri, Biraghi; Maxime Lopez, Mandragora; Nico Gonzalez, Bonaventura, Sottil; Belotti
Roma: Svilar; Mancini, Llorente, Ndicka, Angeliño; Cristante, Paredes, Aouar; Dybala, Lukaku, El Shaarawy
Player statistic
6' | Gianluca Mancini | |||
Luca Ranieri (Assist: Nico González) |
18' | |||
37' | Leandro Paredes | |||
45' | Dean Huijsen |
Giacomo Bonaventura | 57' | |||
58' | Houssem Aouar | |||
Nikola Milenkovic | 64' | |||
68' | Evan Ndicka | |||
Rolando Mandragora | 69' | |||
76' | Tommaso Baldanzi | |||
Cristiano Biraghi | 80' | |||
90+5' | Diego Llorente (Assist: Evan Ndicka) |